Metaphase Arresting Solution

Metaphase Arresting Solution

Metaphase Arresting Solution is a mixture of colchicine/vinblastine sulphate dissolved in PBS. Both compounds inhibit the formation of mitotic spindles and are used to increase the percentage of metaphase cells for chromosome studies. Vinblastine sulphate has been found to be more effective against bone marrows, difficult tumours and problematic tissues with low mitotic indexes, and where colchicine/colcemid appears to be ineffective.



Applications & Benefits
A gentle alternative to colchicine - contains vinblastine
Less toxic to cells
Prevents sensitive cells from lifting off the surface - better chromosome morphology and improved MI
Highly refined solution of colchicine/vinblastine sulphate in PBS, used to increase the percentage of metaphase cells for chromosomal studies. The product is designed to be more effective than colchicine alone for bone marrows, difficult tumours and other problematic tissues.

Metaphase Arresting Solution has been found to be useful for sensitive cultures where cells lift off when colchicine is added. It is gentler than colchicine so cells do not have such an adverse reaction.


Ordering Information
Metaphase Arresting Solution - Powder for 100 ml solutionGGS-JL008347,00 €

Technical Specification

Procedure

see ordering details
1.Use Metaphase Arresting Solution as a direct replacement for colchicine/colcemid in your harvest, keeping volume and incubation time and temperature t
2.After incubation continue with your usual harvest protocols.
Applications & Benefits
Ordering Information
Technical Specifications




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PDF-FileProCell_Brochure.pdf
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PDF-FileProcell A4 leaflet.pdf
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